Will any of the expansion card slot be wired to the GPU?

It should work in PCIe_1 out of the box, as that's the primary slot in pretty much all consumer motherboard for a graphics card I would suggest

You can insert a PCIe x1 card into a PCIe x16 slot, but that card will receive less bandwidth Most GPUs require a PCIe x16 slot to operate at

gpu slot types The Asus GeForce RTX 4060 Ti 8GB Dual OC + SSD Expansion slot does what it says on the

gpu blocking pcie slot The Asus GeForce RTX 4060 Ti 8GB Dual OC + SSD Expansion slot does what it says on the